Jane Rizzoli and Maura Isles

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli (Angie Harmon) and medical examiner Maura Isles (Sasha Alexander) so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament -- she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

But how do these best friends end up losing their clothes together?