Jessica the Fem-dom Mad Scientist

Jessica has secretly developed many unique pills to let her live out her specific fantasies.

The pills:

Enlargement: Increases the size of a man's erect penis by a factor of Jessica's choosing. Anything from a modest 10% increase to a cartoonish 10x, or beyond. Only affects erections because Jessica sees little value in a flaccid cock being large.

Shrinkage: Shrinks the size of a man's penis, hard or soft by a factor of Jessica's choosing, from a slightly evil 25% reduction to a downright diabolical 20x shrinkage. Any man who wrongs Jessica deserves a tiny dick, and doesn't deserve to keep it hidden.

Arousal: Gives uncontrollable erections anywhere from once every few hours, to constantly that wont go down for hours without orgasm. Jessica likes to see a man struggle to hide an erection in public, especially if it's suddenly much larger than he is used to.

Disfunction: Makes it anywhere from somewhat difficult to completely impossible for a man to achieve erection. If she's has already given him a small dick, there is no need to make it hard.

Clothing aversion: Causes extreme discomfort to a man who covers his skin in a certain way. Forcing all clothing to be skin-tight, or overly loose, only allowing certain fabrics or materials to touch certain parts or the body, or even disallowing clothing altogether and making it uncomfortable to even cover with his own hands. Jessica loves to have a look, and loves to make her marks show off to an audience.

Orgasm control: Modulates the amount of stimulation required to achieve orgasm from a loose trigger that goes off at a slight breeze, to requiring hours of furious stimulation to cum, to making it completely impossible to orgasm. A man riding the edge of an orgasm that Jessica knows he can never reach? Even better if it's in public.

Sensitivity: Modulates the amount of sensitivity a man feels from no sensation at all to any touch on the genitals, or even any other exposed skin causing intense stimulation and arousal. If he already can't cum, Jessica doesn't see why he can't have a lot of fun trying.

Weakness: Lowers a man's strength, without altering his physical appearance, anywhere from the lowering it to the strength of an average woman, to the strength of a small child, to not being able to move unassisted. Jessica loves the image of a big muscly man being casually pinned down by a petite woman. Especially if he's naked or she's about to strip him naked.

The Antidote: Cancels out all affects of Jessica's other pills. Can be combined with other pills to keep some effects while removing others. Jessica understands the need to shake things up from time to time.

All of Jessica's pills dissolve almost undetectably in any liquid, leaving just a slight taste that can be masked by stronger flavors. They can be given in any combination at virtually any dosage. They have no effect on women. They can be easily snuck into a man's drink, slipped into a group's dinner, laced in a college's dining hall stock, or even dispersed into a town's water supply.

All effects can be made permanent, set to expire after a given time, set to trigger and un-trigger periodically, or even ratchet up over time. So far only Jessica knows these pills exist, but she might share the knowledge of them, or even share some pills with some trusted friends.