Get a better grasp of exactly how dangerous this could get.

After landing on Hephaestus, swiftly having the delivery unloaded and collecting the payment (thankfully pocketing a nice bonus since you didn't need to pay out any bribes and arrived ahead of schedule) you retreat to your cabin with Rhian and prepare yourself mentally to call Izzy. You really don't want to be in the same history when you tell her that you've lost the majority of her people to an unknown attacker. The only thing that's stopped you from flying very away and calling her from a hidden bunker; is the fact that Rhian is your witness that this clusterfuck wasn't all your fault somehow. So here you sit, finger hovering over the comlink. Finally you let out a sigh and send the call out. Izzy answers seconds later. Her eyes look redder than usual. That does not inspire confidence in you.
"What's wrong?"
You pause briefly and then just say what you need to "Most of your people have been captured."
"WHAT!?" She instantly moves closer to the screen, her face filling it's entirety, eyes almost flashing neon red with fury "How the fuck did this happen Halloway?!"
Rhian moves over to join you on the screen "The ship got attacked on route. We didn't pick anything up till they were already forcing their way onto the ship."
You quickly give all the details you can remember to Izzy; with a few additional comments made from Rhian. For a while you see the anger fade from her face and you can almost see the cogs turning in her head as she starts making her own plans for rescuing her people. However the moment you mention the Drinotol. Seconds later you're watching as one of the women that scares you the most in your life, crumbles weakly before your eyes, the fire fading from her stare. It spooks you almost as much as catching sight of that Drinotol in the first place did.
"Are you sure Halloway?"
"Izzy... you don't mistake something like that."
She nods numbly and turns her head to look at Rhian slightly "You know what this means don't you?"
Rhian shakes her head almost violently in refusal "We can't just leave them Iz! They're my team! They've saved our lives more times than either of us can count an-!"
"Rhian ENOUGH!!"
Rhian instantly shuts up; you look at Isabella's face "What's going on here Izzy? I don't like being kept out of the loop at the best of times and this is apocalyptic levels of bad times."
She lowers her head and doesn't speak for nearly a minute. Finally her head raises back up and she begins to speak; her voice almost monotone, like she's trying not to let her emotions interfere.
"The Cutlasses operate in seven organised groups. Around 100 per business, separated into teams of between five and ten operatives. We make sure they stay completely separate from each other. That way, if one gets attacked we can either withdraw, send reinforcements or go on the attack without weakening anything. The most attacked businesses that we've ever had contend with at one time has been three. Two months ago... all seven were hit at once. 60% of our people were killed outright, 20% were captured and the remainder has been on the run since that night. All we know is that whoever has been making these attacks has heavy weaponry and armour, has a lot of Drinotol on their side and wants to wipe us out completely. Now all we're trying to do is save as many of our people as possible and get them out of this system so we can regroup."
You take a deep breath and run a hand over your face, rubbing your hair furiously "So you're saying that you want us to cut and run?"
Izzy looks at you and slowly nods her head.
"And what happens if I-" Rhian coughs pointedly and glares at you "... WE decide to try and free the others?"
"The other Cutlasses won't help. We've tried mounting rescue ops before. Every one of them has failed. And all we've been left with at the end are emptier pockets and deeper wounds. All you'll get is whatever information we already have."
You slump down low in your seat "... Shit."
Rhian leans forward and click off the comm. You stare at it blankly.
"Derrick... they're my friends. They're all I've got. Please. We need you to help us."
You feel her fingers snake into your hand and wrap around yours. They feel warm and surprisingly soft. You lift your eyes lethargically to look at her face. You've seen it happy, lustful, angry and worried. Now you're watching as she desperately tries to hold herself together. Finally your fingers tighten around hers.
"Okay. It's time to get your people back."